An evil king has risen from the dead to rule the planet once more. But the souls of four guardians are inherited by four heroes, Ban, Max, Claude and Ivan, to fight the evil once again. The guardians wield the ability to shift into anthropomorphic beasts, augmenting more power as they fight their enemies.
- Ban, a judoka. His guardian soul is a Fighting Bull, hence his beast form is a Minotaur. His signature color is red.
- Claude, a swordsman. His guardian soul is a white wolf, and so his beast form is a white werewolf. His human form fights with a Sabre. Yellow is his signature color.
- Max, a fighter with a boxing style. His guardian soul is a black panther, and he predictably transforms into a panther-man. His signature color is blue.
- Ivan, a hunter with a wrestling style. His guardian soul is a bear, so he transforms into a werebear in beast form. His human form fights with a small log. Green is his signature color .
The game's four main characters, Ban, Max, Claude and Ivan, are able to morph into anthropomorphic "beasts" (referred to as Beast Mode) by collecting a golden statue power-up. The power-up drops from either a random chest that falls from the sky, or through an anthropomorphic mouse appearing at random times and supplying the player with either a POWER-UP or a Beast Statue. The mouse will drop power-ups after a certain period of time, or if the player attacks him, similar to the elves in Golden Axe. When the players collect a statue when already in Beast Mode, the character performs a "Screen Attack" which destroys all onscreen enemies (if the statue is collected during a boss fight, the boss is hit hard and usually twice, but they can survive). The enemies are also anthropomorphic animals such as frogs, elephants, lizards, hedgehogs, boars, and others, and include bosses like Baphomet and Ra.